As the prevalence of remote administration tools grows within enterprise infrastructures, the risk of remote administration compromise becomes an increasingly critical concern for organizations. Effective remote administration compromise detection demands a thorough understanding of both authorized and unauthorized remote activities, as well as the ability to differentiate between legitimate support sessions and covert intrusions. This guide examines the nuanced indicators that often precede or accompany unauthorized remote administration, from anomalous network traffic and unusual account activity to unaccounted system changes. By detailing robust investigative techniques and recommended security protocols, it enables IT and security professionals to enhance organizational vigilance and respond decisively to potential threats.